Welcome to Heart Matters – Empowering Heart Health
Healthy LivingInvestigations

Understanding the Coronary Calcium Score: What the Number Really Means

The coronary calcium score is a powerful tool, but it can also lead to confusion and unnecessary worry. In this article, we explore what the number really means, why it is only one part of the story, and how to use it to guide, not dictate your heart health decisions.

Coronary calcium scoring is one of the most widely used tools to assess cardiovascular risk, yet it often causes more confusion and anxiety than clarity. As a cardiologist, I have witnessed firsthand the uncertainty many patients feel when presented with their calcium score. For some, a high number sparks alarm. For others, a score of zero brings false reassurance. The key message I share with every patient is this: you are not defined by a number.

What is a Coronary Calcium Score?

A coronary calcium score is derived from a noninvasive CT scan that measures the amount of calcified plaque in the coronary arteries. These are the arteries that supply blood to the heart muscle. Calcium in the artery walls is a marker of atherosclerosis — the build up of plaque over time.

The scan provides a numerical value, often ranging from 0 (no detectable calcium) to well into the thousands. But it is important to understand that this score is just one part of a much bigger picture.

Why It Can Cause Worry

Many risk calculators used in heart health care are designed to estimate the long term risk of a heart attack or stroke, often expressed as a percentage over five or ten years. While helpful in some respects, these numbers can also unintentionally heighten worry and stress. I have had patients arrive at clinic deeply concerned, convinced their life is on borrowed time because of a high calcium score.

The truth is more nuanced. A high score is a signal to pay attention, not a sentence. Likewise, a score of zero does not always mean you are in the clear.

What the Number Does and Does Not Tell Us

A calcium score reflects the burden of calcified plaque — the hard, rock like deposits that accumulate over time in response to inflammation and damage in the arteries. These are usually stable and less likely to rupture. Ironically, the plaques that are most dangerous are often the soft ones, made up of lipids and inflammatory cells. These are the ones that may not contain any calcium and can still cause a sudden blockage and heart attack.

So yes, you can have a calcium score of zero and still have significant soft plaque that has not yet calcified. This is especially true in younger individuals or people with rapidly progressing disease.

Conversely, I have cared for patients with calcium scores in the thousands who, upon undergoing invasive coronary angiography — the most definitive test for blocked arteries, were found to have no major narrowing at all.

 

[embedyt] https://www.youtube.com/watch?v=L8icWfqT0r8[/embedyt]

Moving Beyond the Score

It is worth repeating: do not let a number dictate your life. Whether your calcium score is zero, 100, or 2000, it is only one marker of risk. What truly matters is what we do with that information.

This includes:

  • Reviewing your full risk profile: blood pressure, cholesterol, diabetes status, smoking history, family history, and lifestyle
  • Understanding your symptoms: Are you experiencing chest discomfort, breathlessness, or fatigue with exertion? These matter more than the scan alone
  • Using additional tests if needed: In some cases, a stress test, coronary CT angiogram, or even an invasive angiogram may be required for further evaluation
  • Focusing on what you can control: Regular activity, heart healthy eating, stopping smoking, managing weight, and using the right medications where needed

A Tool, Not a Verdict

The calcium score is a valuable tool. But it is just that, a tool, not a verdict. It gives us insight into long term risk and can guide decisions on whether to start or intensify treatments like cholesterol lowering medications. But it must always be interpreted in context, alongside clinical judgement and the whole patient story.

Reassurance and Perspective

I often tell my patients that we are in a much stronger position than we used to be. We now have powerful strategies to manage cardiovascular risk. And even if your calcium score is high, that does not mean a heart attack is inevitable. It means we have an opportunity , a chance to take action early and protect your heart.

So if you are worried about your calcium score, please know this: you are not alone, and you are not helpless. With the right approach, you can take control and lead a full and healthy life.

About the author
Cardiologist & Founding Editor

Peter is an interventional cardiologist and the Founding Editor of Heart Matters, a trusted resource for heart health education. With more than 20 years of clinical experience, he is dedicated to making cardiovascular care more understandable and accessible. His work bridges patient care, research, and public education, empowering individuals to take control of their heart health. Professor Barlis is internationally recognised for his contributions to cardiology, with numerous publications and speaking engagements around the world.

Our Youtube Channel

Discover our Heart Matters YouTube channel, where we bring heart health to life. From explaining common conditions and symptoms to discussing the latest research, our engaging videos simplify complex topics, ensuring you have access to valuable knowledge for a healthier heart. Subscribe now and embark on a journey of education, empowerment, and inspiration.

Subscribe to our newsletter and be the first to receive valuable insights, tips, and resources on heart health.

other anti-anginals

When first-line therapies for angina, such as beta blockers, calcium channel blockers, and nitrates, prove inadequate or are not well-tolerated, second-line therapies may be considered.
Perhexiline is a unique medication that enhances the heart's ability to utilize fatty acids for energy, reducing its reliance on oxygen and lowering oxygen demand. This action helps improve blood flow and alleviates chest pain in some patients with refractory angina.
Nicorandil is another second-line option with a dual mechanism of action. It opens potassium channels in smooth muscle cells, causing vasodilation and enhancing coronary blood flow. Additionally, nicorandil also stimulates nitric oxide release, further dilating blood vessels and reducing heart workload.
Trimetazidine is an anti-ischemic agent that improves cardiac efficiency by enhancing glucose metabolism and shifting the heart's energy production to a more oxygen-efficient process. As second-line therapies, these medications offer alternative approaches for managing angina in individuals who do not respond adequately to first-line treatments or those experiencing side effects from other medications.

lipid lowering therapies

Lipid-lowering therapies are essential in managing coronary artery disease (CAD), a condition where the arteries supplying blood to the heart become narrowed. Among the most commonly prescribed treatments are statins, which reduce cholesterol production in the liver and significantly lower the risk of heart attacks and strokes.

Other medications may be used to target different aspects of lipid metabolism:

  • Ezetimibe helps reduce the absorption of cholesterol in the gut
  • Fibrates lower triglyceride levels
  • Niacin can help raise high-density lipoprotein (HDL) cholesterol

In recent years, a newer class of medications known as PCSK9 inhibitors—such as Repatha (evolocumab)—has become available. These drugs block a specific enzyme involved in cholesterol regulation and can dramatically lower LDL cholesterol, particularly in patients who do not achieve target levels with statins alone.

Together, these therapies provide a range of options to personalise treatment and improve cardiovascular outcomes.

Nitrates

Nitrates for Angina Relief

Nitrates are widely used to treat angina and provide quick relief from chest pain. These medications are commonly available as sublingual sprays or tablets, skin patches, and long-acting tablets.

Nitrates work by dilating blood vessels, allowing for increased blood flow and reduced vascular resistance. This reduces the heart’s workload and lowers its oxygen demand, offering prompt relief from angina symptoms.

Sublingual nitrates act quickly and are typically used at the onset of angina symptoms, while patches and long-acting tablets are used for ongoing prevention.

Common side effects include headaches, dizziness, and flushing. These often improve with continued use but should be discussed with a healthcare provider if persistent or bothersome.

calcium channel blockers

Calcium channel blockers, including amlodipine, felodipine, Cardizem (diltiazem), and verapamil, are commonly prescribed for the treatment of angina.

These medications work by inhibiting the influx of calcium into the muscle cells of the heart and blood vessels, causing them to relax. This relaxation leads to the widening of blood vessels, which improves blood flow and reduces blood pressure.

For individuals with angina, calcium channel blockers reduce the heart’s workload and oxygen demand, helping to relieve chest pain and prevent angina episodes.

While effective, they may cause side effects such as headaches, dizziness, facial flushing, and ankle swelling. These effects should be monitored and discussed with your healthcare provider if they persist.

Beta blockers

Beta blockers, such as metoprolol, propranolol, atenolol, carvedilol, and bisoprolol, play a crucial role in managing angina.

These medications work by blocking specific receptors in the heart, which slows the heart rate and reduces the strength of each contraction. This results in a lower oxygen demand by the heart and helps relieve chest pain associated with angina.

Beta blockers are highly effective in both relieving symptoms and preventing angina episodes. However, they may cause side effects in some individuals, including tiredness, worsened asthma symptoms, more vivid dreams, and erectile dysfunction in some males.

It is important to consult your healthcare provider to determine whether beta blockers are a suitable option for your angina and overall heart health.

Anti-platelet Medications

Anti-platelet medications play a crucial role in preventing blood clot formation and reducing the risk of serious cardiovascular events such as heart attacks and strokes. Commonly used agents include aspirin, clopidogrel, and ticagrelor.

 

Aspirin: This well-known medication inhibits platelet activation, reducing the likelihood that platelets will clump together and form clots. It is widely used for both primary and secondary prevention of heart attacks and strokes.

 

Clopidogrel: A potent anti-platelet agent, clopidogrel works by blocking specific receptors on platelets to prevent aggregation. It is commonly prescribed for patients with acute coronary syndrome, those undergoing stent placement, and some individuals with peripheral arterial disease.

 

Ticagrelor: Ticagrelor also inhibits platelet activation and is typically used in the treatment of acute coronary syndrome. It is often prescribed alongside aspirin to provide dual anti-platelet therapy and further reduce the risk of heart-related events.